Sunday, January 31, 2010

Whipple Disease

Saturday, January 30, 2010

Pheochromocytoma

Tuesday, January 26, 2010

Necrotizing Fasciitis

Necrotizing fasciitis is a rare but extremely aggressive, life-threatening soft-tissue infection of the subcutaneous and fascial tissues often encountered in diabetic patients. The muscle tissues are generally spared. Clinical examination of the skin reveals streaking erythema and sometimes small blisters, arising in the region of an incidental puncture wound. Local induration is always found, and occasionally subcutaneous crepitation caused by gas in the soft tissues is encountered. Air in the soft tissues can usually be seen on plain radiographs in gas-producing clostridial infections. Serial exams are necessary to track the leading edge of the infection, which rapidly progresses in the direction of venous drainage. Emergent surgical debridement of devitalized tissues (sometimes necessitating amputation) along with antibiotics and intensive care treatment for hypotension are required to prevent death.